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Trowel: a fast and accurate error correction module for Illumina sequencing reads.

Identifieur interne : 001A36 ( Main/Exploration ); précédent : 001A35; suivant : 001A37

Trowel: a fast and accurate error correction module for Illumina sequencing reads.

Auteurs : Eun-Cheon Lim [Allemagne] ; Jonas Müller [Allemagne] ; Jörg Hagmann [Allemagne] ; Stefan R. Henz [Allemagne] ; Sang-Tae Kim [Allemagne] ; Detlef Weigel [Allemagne]

Source :

RBID : pubmed:25075116

Descripteurs français

English descriptors

Abstract

The ability to accurately read the order of nucleotides in DNA and RNA is fundamental for modern biology. Errors in next-generation sequencing can lead to many artifacts, from erroneous genome assemblies to mistaken inferences about RNA editing. Uneven coverage in datasets also contributes to false corrections.

DOI: 10.1093/bioinformatics/btu513
PubMed: 25075116


Affiliations:


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